Alzheimer’s
• The Potential Therapeutic Effects of THC on Alzheimer's Disease
https://www.ncbi.nlm.nih.gov/pubmed/25024327
• Safety and Efficacy of Medical Cannabis Oil for Behavioral and Psychological Symptoms of Dementia: An-Open Label, Add-On, Pilot Study
https://www.ncbi.nlm.nih.gov/pubmed/26757043
• Emerging Promise of Cannabinoids for the Management of Pain and Associated Neuropathological Alterations in Alzheimer’s Disease
https://www.frontiersin.org/articles/10.3389/fphar.2020.01097/full
Autism
• Real Life Experience of Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy
https://www.nature.com/articles/s41598-018-37570-y
Cancer
• Breast Cancer
A study of breast cancer patients' use of cannabis before, during and after treatment
https://acsjournals.onlinelibrary.wiley.com/doi/abs/10.1002/cncr.33906
• Cannabis and Cancer
• A user’s guide to cannabinoid therapies in oncology
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176373/
• Cannabinoids as therapeutic agents in cancer: current status and future implications
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171598/
• Cannabis for the Management of Cancer Symptoms: THC Version 2.0?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961457/
• Integrating Cannabis Into Clinical Cancer Care For Apetite Stimulation, Nausea, Pain and Peripheral Neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791148/
• Cannabinoids in Glioblastoma Therapy: New Applications for Old Drugs
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964193/
• World’s First Trial to Treat Glioblastoma with Medical Cannabis
(B) https://www.fxmedicine.com.au/content/medicinal-cannabis-brain-cancer-dr-janet-schloss
• Medical Cannabis Use in Glioma Patients Treated at a Comprehensive Cancer Center in Florida
https://www.liebertpub.com/doi/full/10.1089/jpm.2018.0528
• CBD Enriched Cannabis Was More Effective at Killing Leukemia and Paediatric Brainstem Glioma Cancer Cells than THC Varieties
• Medical Cannabis use in Head and Neck Squamous Cell Carcinoma patients treated with radiotherapy
https://link.springer.com/article/10.1007%2Fs00520-016-3180-8
Ovarian Cancer
• Enhancing ovarian cancer conventional chemotherapy through the combination with cannabidiol loaded microparticles
https://www.sciencedirect.com/science/article/abs/pii/S0939641120302113?via%3Dihub
Pancreatic Cancer
• Anticancer Effect of New Cannabinoids Derived from Tetrahydrocannabinolic Acid on PANC-1 and AsPC-1 Human Pancreas Tumor Cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337241/#!po=2.08333
• Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663976/
Cannabinoid Hyperemesis Syndrome
• Cannabinoid hyperemesis syndrome (CHS) is a condition that leads to repeated and severe bouts of vomiting. How rare or common is it?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576702/
Cannabis: A Better Alternative to Benzodiazepines?
• Reduction of Benzodiazepine Use in Patients Prescribed Medical Cannabis
https://www.liebertpub.com/doi/10.1089/can.2018.0020
The Cannabis sativa Versus Cannabis indica Debate: An Interview with Ethan Russo, MD
https://www.liebertpub.com/doi/full/10.1089/can.2015.29003.ebr
CBD
• A Single Dose Of Cannabidiol Reduces Blood Pressure In Healthy Volunteers In A Randomized Crossover Study
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470879/
• CBD: What You Need to Know Before You Try
https://www.cedars-sinai.org/blog/cbd-safe.html
• CBD Oil And Cancer: 9 things to know
• Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Regulate Intraocular Pressure
https://www.ncbi.nlm.nih.gov/pubmed/30550613
• Clinically Significant Drug-Drug Interaction Between Methadone and Cannabidiol
https://pediatrics.aappublications.org/content/early/2020/05/21/peds.2019-3256
• Cannabidiol and Sports Performance: a Narrative Review of Relevant Evidence and Recommendations for Future Research
https://sportsmedicine-open.springeropen.com/articles/10.1186/s40798-020-00251-0
• Cannabidiol for the Treatment of Cannabis Use Disorder: a phase 2a, double-blind, placebo-controlled, randomised, adaptive Bayesian trial
https://pubmed.ncbi.nlm.nih.gov/32735782/
• Cannabidiol Improves Blood Flow to Brain’s Hippocampus
https://neurosciencenews.com/cbd-hippocampus-16806/
• Cannabidiol and Abnormal Liver Chemistries in Healthy Adults: Results of a Phase 1 Clinical Trial
https://ascpt.onlinelibrary.wiley.com/doi/abs/10.1002/cpt.2071
• Cannabidiol Reduces Binge Eating Behavior in Mice
https://helda.helsinki.fi/handle/10138/332343
Colitis
• THC, not CBD, protected against colitis through activation of CB2 receptors and through enterocytes in a mouse model
Consumption Methods
• Explore a variety of options for consuming cannabis: from edibles to topicals and inhalation, this will help guide you to administering cannabis medicine based on your needs and comfort level.
https://www.medicaljane.com/category/cannabis-classroom/consuming-cannabis/#smoking-cannabis
Depression
• The Effectiveness of Cannabis Flower for Immediate Relief from Symptoms of Depression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309674/
Dosing
• Practical considerations in medical cannabis administration and dosing
https://www.sciencedirect.com/science/article/abs/pii/S0953620518300049
Drug Interactions
• Medicinal Cannabis—Potential Drug Interactions
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473892/
• Probable Interaction Between Warfarin and Inhaled and Oral Administration of Cannabis
https://europepmc.org/abstract/MED/31319733
• Delta-9-Tetrahydrocannabinol and Cannabidiol Drug-Drug Interactions
https://www.karger.com/Article/FullText/507998
• With Commercial Cannabis-Based Products Increasingly Being Used in the Community...There Is An Increased Potential For A Drug–Drug Interaction (DDI) Between Cannabis-Based Products and Conventional Treatments
https://www.liebertpub.com/doi/10.1089/can.2020.0053
Effects of Cannabis Smoking on the Lung
https://www.atsjournals.org/doi/full/10.1513/AnnalsATS.201212-127FR
Elder Use
• Epidemiological characteristics, safety and efficacy of medical cannabis in the elderly
https://www.ncbi.nlm.nih.gov/pubmed/29398248
• Medical Cannabis in the Skilled Nursing Facility: A Novel Approach to Improving Symptom Management and Quality of Life
https://www.sciencedirect.com/science/article/pii/S1525861018306625
Endometriosis
• Self-management strategies amongst Australian women with endometriosis: a national online survey
https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-019-2431-x
Epilepsy
• Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767492/
Fibromyalgia
• Medical Cannabis for the Treatment of Fibromyalgia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176373/
• Safety and Efficacy of Medical Cannabis in Fibromyalgia
https://www.ncbi.nlm.nih.gov/pubmed/31195754
• Effect of adding medical cannabis to analgesic treatment in patients with low back pain related to fibromyalgia:an observational cross-over single centre study
https://pdfs.semanticscholar.org/8fb2/0c23fcd56d9140714e95ef5f9f37ebfc451d.pdf
Human Reproduction
• Cannabis smoking linked with higher sperm concentrations
https://www.hsph.harvard.edu/news/press-releases/marijuana-smoking-sperm-counts/
Inflammatory Bowel Diseases
• Chron's and Colitis Foundation
• Use of Medical Cannabis in Patients With Inflammatory Bowel Disease
Migraines
• Emerging Role of (Endo)Cannabinoids in Migraine
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928495/
• Cannabis reduces headache and migraine pain by nearly half
https://www.sciencedaily.com/releases/2019/11/191125100353.htm
https://www.ncbi.nlm.nih.gov/pubmed/31715263
Multiple Sclerosis
• Cannabidiol to Improve Mobility in People with Multiple Sclerosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874292/
• Cannabis for Multiple Sclerosis: Prescriber’s Perspective
• MS and Use of Medical Cannabis: A Retrospective Review Evaluating Symptom Outcomes
https://n.neurology.org/content/92/15_Supplement/P5.2-106
Osteoarthritis
• Cannabis and joints: scientific evidence for the alleviation of osteoarthritis pain by cannabinoids
https://www.ncbi.nlm.nih.gov/pubmed/29635215
Pain
• The Endocannabinoid System, Cannabinoids, and Pain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820295/
• Personal experience and attitudes of pain medicine specialists in Israel regarding the medical use of cannabis for chronic pain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074811/
• A Cost-Effectiveness Model for Adjunctive Smoked Cannabis in the Treatment of Chronic Neuropathic Pain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446169/
• Medical Cannabis for Neuropathic Pain
https://www.ncbi.nlm.nih.gov/pubmed/29388063
• The Impact of Medical Cannabis on Intermittent and Chronic Opioid Users with Back Pain: How Cannabis Diminished Prescription Opioid Usage
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480723/
Parkinson’s
• Marijuana for Parkinson’s Disease?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450681/
Pediatric Use
• Cannabis Medicine in Pediatric Healthcare
• Cannabinoids in Pediatrics
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473390/
Post-Traumatic Stress Disorder
• Cannabidiol in the Treatment of Post-Traumatic Stress Disorder: A Case Series.
https://www.ncbi.nlm.nih.gov/pubmed/30543451
• A review of medical marijuana for the treatment of post-traumatic stress disorder: Real symptom re-leaf or just high hopes?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007739/
Psychiatric Concerns
• Cannabis-Induced Bipolar Disorder with Psychotic Features
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811144/
• Cannabis-Induced Psychosis: A Review
https://www.psychiatrictimes.com/substance-use-disorder/cannabis-induced-psychosis-review/page/0/4
Replacing Opioids With Cannabis
• Daily Cannabis Use Lowers Odds of Using Illicit Opioids Among People Who Have Chronic Pain
Sickle Cell Disease
• Study: Medical marijuana may reduce hospitalizations among patients with sickle cell disease
Spinal Cord Injury
• Utilization of Medicinal Cannabis for Pain by Individuals with Spinal Cord Injury
https://www.nature.com/articles/s41394-019-0208-6
Terpenes/Terpenoids And Their Importance
• The healing power of cannabis most likely resides in terpenes/terpenoids and phytocannabinoids, of which particular compounds, their quantity and ratio to each other play the most important role in the treatment of particular diseases. It should be emphasized that flavonoids, flavonoid glycosides, polyphenol and other biodynamic compounds also contribute.
https://www.karger.com/Article/Pdf/509733
Viewpoints
• Harvard Medical School: Medical Cannabis
https://www.health.harvard.edu/blog/medical-marijuana-2018011513085
• Mayo Clinic Q & A: Treatment With Medical Cannabis
https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-treatment-with-medical-cannabis/
• Perspectives on Cannabis Research—Barriers and Recommendations
• Why Doctors Know Almost Nothing About The Health Effects Of Cannabis
https://www.aamc.org/news-insights/why-doctors-know-almost-nothing-about-health-effects-marijuana
• You’re Missing The Full Story On Medical Cannabis - Joseph (Yossi) Tam, DMD, PhD, Director of the Multidisciplinary Center for Cannabinoid Research at Hebrew University of Jerusalem
https://blogs.timesofisrael.com/youre-missing-the-full-story-on-medical-cannabis/
Withdrawl
• If Cannabis Becomes A Problem: How To Manage Withdrawal
• More Than Half of People Using Cannabis for Pain Experience Multiple Withdrawal Symptoms